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Analgesic and central depressor effects of the dichloromethanol extract from Schinus molle L.

✍ Scribed by M. D. Barrachina; R. Bello; M. A. Martínez-Cuesta; E. Primo-Yúfera; J. Esplunges

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
86 KB
Volume
11
Category
Article
ISSN
0951-418X

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✦ Synopsis

The analgesic and central depressor effects of the dichloromethanol extract of Schinus molle L. were analysed in in vivo models. This extract showed low acute toxicity, CNS depressor activity and analgesic effect. Following further fractionation, the hexane/dichloromethane (75/25) fraction showed the most interesting results. Thus, this fraction caused a total inhibition of motor activity and significantly reduced the threshold of pain to chemical stimulus.

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