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Analgesic Actions of Corticotropin-Releasing Factor (CRF) on Somatic Pain Sensitivity: Involvement of Glucocorticoid and CRF-2 Receptors

✍ Scribed by N. I. Yarushkina; T. R. Bagaeva; L. P. Filaretova


Publisher
Springer US
Year
2009
Tongue
English
Weight
148 KB
Volume
39
Category
Article
ISSN
0097-0549

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## Abstract Corticotropin‐releasing factor (CRF), the principal regulator of the hypothalamus‐pituitary‐adrenal (HPA) axis, also modulates the inflammatory response directly, via its effect on mast cells and macrophages. On macrophages, it augments production of lipopolysaccharide (LPS)‐induced pro