An update on methotrexate pharmacogenetics in rheumatoid arthritis
β Scribed by Ranganathan, Prabha
- Book ID
- 118035740
- Publisher
- Future Medicine
- Year
- 2008
- Tongue
- English
- Weight
- 382 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1462-2416
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π SIMILAR VOLUMES
Methotrexate (MTX) is effective in the treatment of refractory rheumatoid arthritis (RA). Its use by practitioners has become commonplace, even though it is not yet approved by the Food and Drug Administration for this use. One might assume, therefore, that there is a general understanding, among pr
Children with juvenile rheumatoid arthritis (JRA) have been reported to require higher doses (per kg body weight) of methotrexate (MTX) than adults with rheumatoid arthritis to control their disease. The purpose of the present study was to characterise the plasma pharmacokinetics of MTX and its majo