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An unusual adverse reaction to Ro 10-9359

โœ Scribed by K. Moulopoulou-Karakitsou; Myron Mavrikakis; M. Anastasiou-Nana


Book ID
108657390
Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
55 KB
Volume
104
Category
Article
ISSN
0007-0963

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An aromatic retinoid Ro 10-9359 is metabolized after absorption from intestine to form Ro 10-1670 which is an active therapeutic compound. The epidermal keratinocytes, a main target tissue of retinoid therapy in dermatology, was examined in the capacity to metabolize the retinoid. The culture of hum