Metabolism of an aromatic retinoid Ro 10
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Yukio Kitano; Natsuko Okada; Naoko Nagase
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Article
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1982
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Springer-Verlag
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English
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An aromatic retinoid Ro 10-9359 is metabolized after absorption from intestine to form Ro 10-1670 which is an active therapeutic compound. The epidermal keratinocytes, a main target tissue of retinoid therapy in dermatology, was examined in the capacity to metabolize the retinoid. The culture of hum