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An Unidentified, Filtrable Agent Isolated from Transplanted Human Tumors

✍ Scribed by Helene W. Toolan, Gilbert Dalldorf, Marion Barclay, Satish Chandra and Alice E. Moore

Book ID
123656318
Publisher
National Academy of Sciences
Year
1960
Tongue
English
Weight
146 KB
Volume
46
Category
Article
ISSN
0027-8424

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A tumor rejection antigen (TATA), obtained from the cytosol of a BALB/c mKSA sarcoma induced by SV40 virus, has been partially purified. This partially purified antigen is strikingly immunogenic against mKSA, providing more than 90% inhibition of growth at levels of 10-30 pg. This antigen preparatio