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An unexpected role of plasminogen activator inhibitor-type 1 (PAI-1) in renal fibrosis

✍ Scribed by Huang, Yufeng; Noble, Nancy


Book ID
109067183
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
36 KB
Volume
67
Category
Article
ISSN
0085-2538

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πŸ“œ SIMILAR VOLUMES


TYPE-1 PLASMINOGEN ACTIVATOR INHIBITOR I
✍ WAGNER, STEPHAN N.; ATKINSON, MICHAEL J.; THANNER, STEPHANIE; SCHMITT, MANFRED; πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 597 KB

In experimental models, plasminogen activator-mediated degradation of the extracellular matrix is inhibited by type-1 plasminogen activator inhibitor (PAI-1). PA14 has also been shown to protect tumour stromal tissue from autoproteolytic activities and may thus substantially promote tumour growth an