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An unexpected effect of ATP on the ratio between activity and phosphoenzyme level of Na+/K+-ATPase in steady state

✍ Scribed by Pablo J. Schwarzbaum; Sergio B. Kaufman; Rolando C. Rossi; Patricio J. Garrahan

Book ID
115730586
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
718 KB
Volume
1233
Category
Article
ISSN
0005-2736

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✍ Dennis J. Pillion; Lamar Moree; Hector Rocha; David H. Pashley; Joseph Mendicino πŸ“‚ Article πŸ“… 1977 πŸ› Springer 🌐 English βš– 599 KB

The effects of diamide were studied in rat kidney cortical tissue. It was found that diamide increased oxidized glutathione levels and inhibited Na+-K+-ATPase activity. Consistent with this finding was the observation that diamide compromised the sodium gradients maintained in renal cortical slices.