An optimal time control problem for the
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E. Beretta; F. Solimano
📂
Article
📅
1993
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Springer
🌐
English
⚖ 693 KB
The problem of optimal dosage is studied for the administration of ddCyd using erythrocytes as carriers and bioreactors. The volume of erythrocytes and the initial amount of drug to be loaded have to be determined in such a way that the duration of the therapeutic effect is maximized without exceedi