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An optimal time control problem for the administration of 2′,3′-dideoxycytidine by using red blood cells as bioreactors

✍ Scribed by E. Beretta; F. Solimano


Book ID
112754280
Publisher
Springer
Year
1993
Tongue
English
Weight
670 KB
Volume
55
Category
Article
ISSN
1522-9602

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An optimal time control problem for the
✍ E. Beretta; F. Solimano 📂 Article 📅 1993 🏛 Springer 🌐 English ⚖ 693 KB

The problem of optimal dosage is studied for the administration of ddCyd using erythrocytes as carriers and bioreactors. The volume of erythrocytes and the initial amount of drug to be loaded have to be determined in such a way that the duration of the therapeutic effect is maximized without exceedi