An Optical Switch for a Motor Protein
β Scribed by Dr. Xiang Li; Prof. Dr. Tarun M. Kapoor
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 155 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1439-4227
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Incorporation of an unnatural amino acid containing a photolabile group in the side chain allows specific interactions between two proteins to be prevented. The photocaged ras protein in which Aspβ38 has been substituted by its Ξ²-nitrobenzyl ester (Nb) is unable to interact with its effector protein
## Abstract A significant challenge in utilizing kinesin biomolecular motors in integrated nanoscale systems is the ability to regulate motor function in vitro. Here we report a versatile mechanism for reversibly controlling the function of kinesin biomolecular motors independent of the fuel supply