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An open-label safety and efficacy study of an anti-CD20 antibody (rituximab, Rituxan) for anti-B-cell therapy in the treatment of systemic lupus erythematosus

✍ Scribed by RA Eisenberg, S Khan, J Stansberry, D Tsai, S Kolasinski, E Rieder…


Book ID
120707235
Publisher
BioMed Central
Year
2004
Tongue
English
Weight
391 KB
Volume
6
Category
Article
ISSN
1478-6354

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✍ Martin Aringer; Winfried B. Graninger; Günter Steiner; Josef S. Smolen 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 116 KB 👁 1 views

## Abstract ## Objective To investigate the safety of therapeutic tumor necrosis factor α (TNFα) blockade in patients with systemic lupus erythematosus (SLE), in whom this proinflammatory cytokine is significantly increased and may be involved in the disease pathogenesis. ## Methods In an open‐l