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An ionic liquid mediated one-pot synthesis of substituted thiazolidinones and benzimidazoles

✍ Scribed by Ashok K. Yadav; Manoj Kumar; Tripti Yadav; Renuka Jain


Publisher
Elsevier Science
Year
2009
Tongue
French
Weight
192 KB
Volume
50
Category
Article
ISSN
0040-4039

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✦ Synopsis


3,4a]benzimidazoles 2-Mercaptoacetic acid and aromatic aldehyde a b s t r a c t An expeditious one-pot synthesis of 2,3-diaryl/2-aryl-3-heteroaryl-1,3-thiazolidin-4-ones and 1-aryl-1H,3H-thiazolo[3,4-a]benzimidazoles have been accomplished by condensing hetero/aromatic amine, 2-mercaptoacetic acid, aromatic aldehyde and 1,2-phenylenediamine, 2-mercaptoacetic acid and aromatic aldehyde, respectively, in ionic liquids, viz, 1-butyl-3-methyl-imidazolium tetrafluoroborate and 1-methoxyethyl-3-methylimidazolium trifluoroacetate.


πŸ“œ SIMILAR VOLUMES


One-pot synthesis of polyfunctionally su
✍ Mohareb, Rafat M. ;Sherif, Sherif M. ;Abdel-Aal, Fatma A. M. ;Sayed, Nadia I. A. πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 346 KB

## Abstract The reaction of phenyl isothiocyanate with the active methylene reagents 1a–e gives the nonisolable 1:1 adducts 2a–e. The latter react with α‐halogenated compounds, e.g. phenacyl bromide, bromoacetyl bromide, chloroacetone, chloroacetonitrile and some hydrazonoyl halides to give the cor