An ionic liquid mediated one-pot synthesis of substituted thiazolidinones and benzimidazoles
β Scribed by Ashok K. Yadav; Manoj Kumar; Tripti Yadav; Renuka Jain
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- French
- Weight
- 192 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
3,4a]benzimidazoles 2-Mercaptoacetic acid and aromatic aldehyde a b s t r a c t An expeditious one-pot synthesis of 2,3-diaryl/2-aryl-3-heteroaryl-1,3-thiazolidin-4-ones and 1-aryl-1H,3H-thiazolo[3,4-a]benzimidazoles have been accomplished by condensing hetero/aromatic amine, 2-mercaptoacetic acid, aromatic aldehyde and 1,2-phenylenediamine, 2-mercaptoacetic acid and aromatic aldehyde, respectively, in ionic liquids, viz, 1-butyl-3-methyl-imidazolium tetrafluoroborate and 1-methoxyethyl-3-methylimidazolium trifluoroacetate.
π SIMILAR VOLUMES
## Abstract The reaction of phenyl isothiocyanate with the active methylene reagents 1aβe gives the nonisolable 1:1 adducts 2aβe. The latter react with Ξ±βhalogenated compounds, e.g. phenacyl bromide, bromoacetyl bromide, chloroacetone, chloroacetonitrile and some hydrazonoyl halides to give the cor