𝔖 Bobbio Scriptorium
✦   LIBER   ✦

An investigation of the effects of subthalamic nucleus stimulation on acoustic measures of voice

✍ Scribed by Christopher Dromey; Rajeev Kumar; Anthony E. Lang; Andres M. Lozano

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
114 KB
Volume
15
Category
Article
ISSN
0885-3185

No coin nor oath required. For personal study only.

✦ Synopsis

Seven patients with Parkinson's disease were implanted with deep brain stimulators to provide chronic electrical stimulation to the subthalamic nucleus bilaterally. Acoustic recordings and neurologic assessments were undertaken before surgery in the medication-off and medication-on conditions and after surgery with and without electrical stimulation in the medication-off and medication-on conditions. The data showed significant improvements in limb motor performance in response to medication before surgery and when the subthalamic nucleus was stimulated after surgery. Six months after surgery, there were small but statistically significant increases in sound pressure level and fundamental frequency variability in response to stimulation in the medication-on condition. No other statistically significant speech changes were measured. These findings are consistent with several other studies that have reported disparity between limb and speech improvements after neurosurgical intervention for Parkinson's disease.

πŸ“œ SIMILAR VOLUMES

An investigation into the effect of spat
An investigation into the effect of spatial scale on the performance of a one-dimensional water balance model
✍ T. J. Jolley; H. S. Wheater πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 294 KB πŸ‘ 1 views

Land surface parameterizations used in atmospheric general circulation models (AGCMs) are one dimensional representations of the transfer of energy and water vapour at the earth's surface over grid squares that are typically of the order of 10 4 km 2 . It is known, however, that climate variables an

An investigation of the effect of patern
An investigation of the effect of paternal occupation group at conception on birth weight and gestational age
✍ Katherine M. Shea; Alexandra Farrow; Ruth Little; ALSPAC Study Team πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 45 KB πŸ‘ 1 views

The occupational histories of fathers were collected prospectively as part of the Avon Longitudinal Study of Pregnancy and Childhood (ALSPAC), and were used to investigate the association of paternal job title with a baby's birth weight and gestational age. The analysis cohort consisted of 4,795 sin

Toughening of Epoxy Resins with Thermopl
Toughening of Epoxy Resins with Thermoplastics: 3. An Investigation into the Effects of Composition on the Properties of Epoxy Resin Blends
✍ Hourston, D. J.; Lane, J. M.; Zhang, H. X. πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 454 KB πŸ‘ 2 views

Three di †erent epoxy resins, based on the diglycidylether of bisphenol A (DGEBA), triglycidyl-p-aminophenol (TGPAP) and tetraglycidyldiaminodiphenylmethane (TGDDM), which are di-, tri-and tetrafunctional, respectively, were mixed in varying proportions and cured with both 3,3@-diaminodiphenylsulpho