An intramolecular diels-alder approach to the galanthan ring system
β Scribed by D.J. Morgans Jr.; Gilbert Stork
- Publisher
- Elsevier Science
- Year
- 1979
- Tongue
- French
- Weight
- 186 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
A novel "phenylbutadiene + A*-pyrroline" intramolecular cycloadditlon has been used to construct a functlonallzed galanthan.
Construction of the galanthan ring system (L), common to many Amaryllidacaea alkaloids1
(lycorine , 2, for example) has been the focus of many studies
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Polycyclic indolic compounds containing the [6,5,6,5,6] ring system were prepared via an intramolecular furan Diels-Alder reaction of a,b-unsaturated amides generated by the N-acylation of 1-(2-furyl)-b-tetrahydrocarbolines. This chemistry can provide access to D( 14)-noryohimban derivatives by expl
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