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An Integrated in Silico Analysis of Drug-Binding to Human Serum Albumin

✍ Scribed by Estrada, Ernesto; Uriarte, Eugenio; Molina, Enrique; Simón-Manso, Yamil; Milne, George W. A.

Book ID
120456049
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
889 KB
Volume
46
Category
Article
ISSN
0095-2338

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✍ Gonzalo Colmenarejo 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 591 KB

## Abstract Drug binding to Human Serum Albumin (HSA) is an area of intense research. The pharmacokinetics and pharmacodynamics of drugs are strongly affected by their binding to this protein. In this article, the field is reviewed, as well as our models to predict drug‐binding affinities to HSA fr