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An insertion/deletion polymorphism in the angiotensin converting enzyme gene is associated with both brain substance P contents and affective disorders

✍ Scribed by Tadao Arinami; Li Liming; Hiroshi Mitsushio; Masanari Itokawa; Hideo Hamaguchi; Michio Toru


Book ID
118510787
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
557 KB
Volume
40
Category
Article
ISSN
0006-3223

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A recent Japanese study on the angiotensin I converting enzyme gene (ACE) insertion/ deletion polymorphism reported that both the D allele (P < 0.02) and the DD genotype (P < 0.002) were significantly more frequent in affective disorder cases than in controls [Arinami et al., 1996: Biol Psychiatry 4

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