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An informative polymorphism detectable by polymerase chain reaction at the 3′ end of the dystrophin gene

✍ Scribed by C. Oudet; R. Heilig; J. L. Mandel


Publisher
Springer
Year
1990
Tongue
English
Weight
22 KB
Volume
85
Category
Article
ISSN
0340-6717

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An informative polymorphism detectable b
✍ C. Oudet; R. Heilig; J. L. Mandel 📂 Article 📅 1990 🏛 Springer 🌐 English ⚖ 342 KB

A fragment that contains a (CA)n sequence from the 3' untranslated region of the dystrophin gene can be amplified by the polymerase chain reaction and shows length polymorphism in a Caucasian population. The two common alleles differ by 4bp. This new genetic marker has a heterozygosity of about 35%