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An informative MspI polymorphism detected at the D21S16 locus

โœ Scribed by G. Camp; A. Vandenberghe; C. Broeckhoven


Book ID
104699059
Publisher
Springer
Year
1990
Tongue
English
Weight
91 KB
Volume
85
Category
Article
ISSN
0340-6717

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The D21S13 locus has shown linkage to a gene for familial Alzheimer disease (FAD) on chromosome 21 (St. George-Hyslop et al. 1987). The limited informativeness of probes for this locus have hindered precise mapping of the FAD locus and analysis of nonallelic heterogeneity in FAD (Schellenberg et al.