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An in vivo investigation into the suitability of pH dependent polymers for colonic targeting

โœ Scribed by Marianne Ashford; John T. Fell; David Attwood; Harbans Sharma; Philip J. Woodhead

Book ID
113366333
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
529 KB
Volume
95
Category
Article
ISSN
0378-5173

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Gastrointestinal performance of tablets coated with pH responsive acrylic polymers (Eudragit) was investigated in human volunteers. Tablet cores were coated with Eudragit S dissolved in ethanol (organic), Eudragit S aqueous dispersion (aqueous), or Eudragit FS aqueous dispersion. Eight fasted volunt