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An in vitro investigation into the suitability of pH-dependent polymers for colonic targeting

✍ Scribed by Marianne Ashford; John T. Fell; David Attwood; Philip J. Woodhead


Book ID
113366272
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
347 KB
Volume
91
Category
Article
ISSN
0378-5173

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Gastrointestinal performance of tablets coated with pH responsive acrylic polymers (Eudragit) was investigated in human volunteers. Tablet cores were coated with Eudragit S dissolved in ethanol (organic), Eudragit S aqueous dispersion (aqueous), or Eudragit FS aqueous dispersion. Eight fasted volunt