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An in vitro method for assay of hormone or agonist-stimulated lipase activity

✍ Scribed by Donald J. Fretland; Peter S. Cammarata

Book ID
113301882
Publisher
Elsevier Science
Year
1987
Weight
576 KB
Volume
28
Category
Article
ISSN
0262-1746

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The problem of activation of cyclophosphamide (CY) for an in vitro chemosensitivity assay was studied using the B16 melanoma. The efficacy of the S9 hepatic microsomal fraction in vitro was compared with activation by passage of drug in vivo. The effect of CY was assayed by inhibition of tritiated t