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An in vitro investigation of endocrine disrupting effects of the mycotoxin alternariol

✍ Scribed by Frizzell, Caroline; Ndossi, Doreen; Kalayou, Shewit; Eriksen, Gunnar S.; Verhaegen, Steven; Sørlie, Morten; Elliott, Christopher T.; Ropstad, Erik; Connolly, Lisa


Book ID
121189998
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
760 KB
Volume
271
Category
Article
ISSN
0041-008X

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Novel oxidative in vitro metabolites of
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## Abstract The __Alternaria__ toxins alternariol (AOH; 3,7,9‐trihydroxy‐1‐methyl‐6__H__‐benzo[__c__]chromen‐6‐one) and alternariol methyl ether (AME, 3,7‐dihydroxy‐9‐methoxy‐1‐methyl‐6__H__‐benzo[__c__]chromen‐6‐one) are common contaminants of food and feed, but their oxidative metabolism in mamma

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✍ Britta Burkhardt; Judith Wittenauer; Erika Pfeiffer; Ute M. D. Schauer; Manfred 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 212 KB

## Abstract **Scope:** Monohydroxylation of alternariol (AOH) and alternariol‐9‐methyl ether (AME) has previously been reported as a prominent metabolic route under cell‐free conditions. This pathway gives rise to several catechol metabolites and may therefore be of toxicological relevance. **Meth