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An in vitro approach to study cellular kinetics of drugs

โœ Scribed by Maikel Raghoebar; Jan A.M. Huisman; Wim B. Van den Berg; Cees A.M. Van Ginneken

Book ID
119086264
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
879 KB
Volume
18
Category
Article
ISSN
0160-5402

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Drug partitioning III. Kinetics of drug
Drug partitioning III. Kinetics of drug transfer in an in vitro model for drug absorption
โœ James T. Doluisio; Joseph V. Swintosky ๐Ÿ“‚ Article ๐Ÿ“… 1965 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 493 KB ๐Ÿ‘ 1 views

The kinetics of drug transfer from a buffered aqueous phase (compartment A) through a lipid phase (compartment B ) to another aqueous buffered phase (compartment C) are reported. These kinetics are obtained from an in vifm model system which in important respects mimics drug transfer during the abso