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An in vitro and in vivo study of the conversion of eicosa-11, 14-dienoic acid to eicosa-5,11,14-trienoic acid and of the conversion of eicosa-11-enoic acid to eicosa-5,11-dienoic acid in the rat

✍ Scribed by David Ullman; Howard Sprecher

Book ID
115736255
Publisher
Elsevier Science
Year
1971
Tongue
English
Weight
894 KB
Volume
248
Category
Article
ISSN
0005-2760

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✍ W. R. Pilgrim; P. Nedoncelle; B. Shroot; J. Maignan; S. Restlé; L'Oréal 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 French ⚖ 303 KB

## Abstract A four step synthesis of [5,6‐^14^C]‐eicosa‐5,8,11‐triynoic acid (1) from [^14^C]‐labelled acetylene is described. [^14^C~2~]‐acetylene was converted to 5‐chloro‐[1,2‐^14^C]‐pentyne via reaction of its monolithium salt with 3‐bromo‐1‐chloropropane. The doubly labelled 5‐chloropentyne th