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An improved synthesis of pyrido[2,3-d]pyrimidines

โœ Scribed by Tsuneo Itoh; Ikuko Fujii; Yasuo Tomii; Ichiro Ishikawa; Hamo Ogura; Yoshihisa Mizuno; Norio Kawahara


Book ID
112128725
Publisher
Journal of Heterocyclic Chemistry
Year
1987
Tongue
English
Weight
187 KB
Volume
24
Category
Article
ISSN
0022-152X

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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

Synthesis of pyrido[2,3-d]pyrimidines fr
โœ Francisco Perandones; Josรฉ L. Soto ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Journal of Heterocyclic Chemistry ๐ŸŒ English โš– 568 KB

## Abstract 2โ€Methoxyโ€4โ€aminoโ€5โ€pyrimidinecarbaldehyde (2a) as well as its 6โ€methyl 2b and 6โ€phenyl derivatives 2c were prepared by reduction of the corresponding aminopyrimidinecarbonitriles 1. Catalytic hydrogenation of 1a, 1b gives 5โ€hydroxymethylpyrimidines 3a, 3b; under the same conditions 1c