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An improved rearranged Human Papillomavirus Type 16 E7 DNA vaccine candidate (HPV-16 E7SH) induces an E7 wildtype-specific T cell response

✍ Scribed by Peter Öhlschläger; Michaela Pes; Wolfram Osen; Matthias Dürst; Achim Schneider; Lutz Gissmann; Andreas M. Kaufmann


Book ID
116958679
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
388 KB
Volume
24
Category
Article
ISSN
0264-410X

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Although many clinical trials on human papillomavirus (HPV) therapeutic vaccines have been performed, clinical responses have not been consistent. We have addressed mucosal cytotoxic cellular immune responses to HPV16 E7 after oral immunization of mice with recombinant Lactobacillus casei expressing