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Enhancement of human papillomavirus (HPV) type 16 E6 and E7-specific T-cell immunity in healthy volunteers through vaccination with TA-CIN, an HPV16 L2E7E6 fusion protein vaccine

✍ Scribed by A de Jong; T O’Neill; A.Y Khan; K.M.C Kwappenberg; S.E Chisholm; N.R Whittle; J.A Dobson; L.C Jack; J St Clair Roberts; R Offringa; S.H van der Burg; J.K Hickling


Book ID
117431091
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
143 KB
Volume
20
Category
Article
ISSN
0264-410X

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✍ Ricardo Rosales; Mario López-Contreras; Roberto Risco Cortes 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 142 KB 👁 1 views

## Abstract Human papillomavirus (HPV) infection is associated with cervical cancer. The E2 and E1 papillomavirus proteins are expressed at the early stage of infection and regulate DNA replication. The E2 protein activates and represses transcription from different HPVs promoters. At some stage wh