Two methods have been developed for the synthesis of tetradeuterated buspirone. reaction of 1-(2-pyrimidinyl)piperazine-3,3,5,5-d4 or 1-(2-pyrirnidinyl). piperazine-2,2,3,3, -d, with 8-(bromobutyl)-8-azaspiro( 4.5]decane-7,9dione in refluxing acetonitrile.
โฆ LIBER โฆ
An improved multigram synthesis of tetradeuterated buspirone
โ Scribed by S. C. Vashishtha; G. McKay; K. K. Midha
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- French
- Weight
- 156 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0022-2135
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