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An improved 3-D Look–Locker imaging method for T1 parameter estimation

✍ Scribed by Ken Nkongchu; Giles Santyr


Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
343 KB
Volume
23
Category
Article
ISSN
0730-725X

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✦ Synopsis


The 3-D Look-Locker (LL) imaging method has been shown to be a highly efficient and accurate method for the volumetric mapping of the spin lattice relaxation time T(1). However, conventional 3-D LL imaging schemes are typically limited to small tip angle RF pulses (5 degrees ), thereby improving the SNR and the accuracy of the method. In phantom studies, a mean T(1) measurement accuracy of less than 2% (0.2-3.1%) using a tip angle of 10 degrees was obtained for a range of T(1) from approximately 300 to 1,700 ms with a measurement time increase of only 15%. This accuracy compares favorably with the conventional 3-D LL method that provided an accuracy between 2.2% and 7.3% using a 5 degrees flip angle.


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