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An Expeditious Synthesis of 4(5) [3-Aminopropyl] Imidazole

โœ Scribed by Adger, Brian M.; Surtees, John

Book ID
121400503
Publisher
Taylor and Francis Group
Year
1987
Tongue
English
Weight
173 KB
Volume
17
Category
Article
ISSN
0039-7911

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โœ Dilip D. Dhavale; Vinod D. Chaudhari; Jayant N. Tilekar ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 101 KB

A practical approach for the synthesis of the (2S,3S,4R)-trihydroxyazepane 1d has been reported. Starting from a-D-xylo-pentodialdose, readily available from D-glucose, the sequence involves Wittig olefination and reductive amination as key steps.