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An expedient synthesis of 2,4,5-trisubstituted 1,4-pentadienes from Baylis–Hillman adducts via the Pd-catalyzed decarboxylation–elimination protocol

✍ Scribed by Ko Hoon Kim; Eun Sun Kim; Jae Nyoung Kim

Book ID
108285619
Publisher
Elsevier Science
Year
2009
Tongue
French
Weight
272 KB
Volume
50
Category
Article
ISSN
0040-4039

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An efficient synthetic method of poly-substituted pyridines was developed. Various poly-substituted pyridines were prepared from the combination of Baylis-Hillman adducts (3 carbons), activated methylene compounds (2 carbons) and ammonium acetate (1 nitrogen) via [3+2+1] annulation protocol in good

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