An expedient one-pot synthesis of novel 10-substituted 9-aminophenanthrenes
โ Scribed by Christophe Rochais; Rodrigue Yougnia; Patrick Dallemagne; Sylvain Rault
- Book ID
- 108285654
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- French
- Weight
- 816 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0040-4039
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## Abstract A synthesis of quinoline derivatives is described __via__ reaction between ethyl bromopyruvate (=ethyl 3โbromoโ2โoxopropanoate), acetylenedicarboxylate, and isatin (=1__H__โindoleโ2,3โdione) in the presence of NaH as a base. Also, these reactions were performed without ethyl bromopyruva
## Abstract A oneโpot SuzukiโMiyaura crossโcoupling/DieckmannโThorpe ring closure protocol under microwave irradiation allows the introduction of diversity on various positions of the phenanthrene ring system.