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An example of merged bimolecular substitution and elimination

✍ Scribed by E.L. Eliel; R.S. Ro


Book ID
103397647
Publisher
Elsevier Science
Year
1958
Tongue
French
Weight
165 KB
Volume
2
Category
Article
ISSN
0040-4020

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## A Concise Asymmetric Synthesis of the Pheromone 1-Methylcyclohex-2-enol (IV) via a "Merged Substitution-Elimination Reaction". -The title compound (III) is prepared from cyclohexene (I) via Sharpless asymmetric dihydroxylation using AD-mix-Ξ², tosylation and an unexpected elimination reaction.