An Evaluation of Peptide-Bond Isosteres
โ Scribed by Amit Choudhary; Prof. Ronald T. Raines
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 661 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1439-4227
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Olefinic analogues of effective peptide-based catalysts for the kinetic resolution of functionalized racemic secondary alcohols have been synthesized. The isosteric replacement of the peptide amide bond in 1 with an (E)-alkene to form 2 has enabled the evaluation of the kinetic role of particular am
Methyl-and (Trifluoromethyl) alkene Peptide Isosteres: Synthesis and Evaluation of Their Potential as ฮฒ-Turn Promoters and Peptide Mimetics. -Enantioselective synthetic approaches toward L-Ala-D-Ala (or enantiomeric) dipeptide isosteres are presented, including for the first time the preparation o