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An evaluation of an angiotensin-converting enzyme gene polymorphism and the risk of arterial thrombosis in patients with the antiphospholipid syndrome

✍ Scribed by Nerys M. Lewis; Kazuaki Katsumata; Tatsuya Atsumi; M. Lourdes Sanchez; Fredeswinda I. Romero; M. Laura Bertolaccini; Andreas Funke; Olga Amengual; Munther A. Khamashta; Graham R. V. Hughes


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
32 KB
Volume
43
Category
Article
ISSN
0004-3591

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No association of an insertion/deletion
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A recent Japanese study on the angiotensin I converting enzyme gene (ACE) insertion/ deletion polymorphism reported that both the D allele (P < 0.02) and the DD genotype (P < 0.002) were significantly more frequent in affective disorder cases than in controls [Arinami et al., 1996: Biol Psychiatry 4

The 4G/5G polymorphism of the type 1 pla
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## Objective: To investigate the relationship between the 4g/5g polymorphism of the type 1 plasminogen activator inhibitor (pai-1) gene and thrombotic manifestations in patients with antiphospholipid syndrome (aps). ## Methods: We studied a total of 247 patients included in the following 4 groups