An European inter-laboratory validation of alternative endpoints of the murine local lymph node assay: 2nd round
โ Scribed by G. Ehling; M. Hecht; A. Heusener; J. Huesler; A.O. Gamer; H. van Loveren; Th. Maurer; K. Riecke; L. Ullmann; P. Ulrich; R. Vandebriel; H.-W. Vohr
- Book ID
- 108287194
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 112 KB
- Volume
- 212
- Category
- Article
- ISSN
- 0300-483X
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๐ SIMILAR VOLUMES
The murine local lymph node assay (LLNA) is a well-established alternative to the guinea pig maximization test (GPMT) or Buehler test (BT) for the assessment of the skin sensitizing ability of a drug, cosmetic material, pesticide or industrial chemical. Instead of radioisotope using in this method,
The local lymph node assay (LLNA) assesses the sensitizing activity of chemicals by measurement of primary lymphocyte proliferation in lymph nodes draining the site of application. In this final inter-laboratory study the consistency of LLNA results between laboratories and with guinea pig maximizat