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An endogenous retrovirus mediating deletion of αβ T cells?

✍ Scribed by Woodland, David L.; Happ, Mary Pat; Gollob, Kenneth J.; Palmer, Ed

Book ID
109767202
Publisher
Nature Publishing Group
Year
1991
Tongue
English
Weight
268 KB
Volume
349
Category
Article
ISSN
0028-0836

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In B cells the loci encoding immunoglobulin chains usually show allelic exclusion; a given B cell transcribes and translates only one productively rearranged allele of the heavy and light chain loci. This ensures that each B cell expresses only one antigen receptor. The loci encoding T-cell receptor