An enantioselective synthesis of the cyclopentene fragment of nucleoside Q

✍ Scribed by Kyung-Hee Kim; Marvin J. Miller

• Publisher: Elsevier Science
• Year: 2003
• Tongue: French
• Weight: 116 KB
• Volume: 44
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(03)00973-0

✦ Synopsis

An enantioselective synthesis of (3S,4R,5S)-(+)-3-amino-4,5-dihydroxycyclopentene, a segment of nucleoside Q and Q base, is reported utilizing an amino acid-derived acylnitroso Diels-Alder cycloaddition.