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An enantiodivergent formal synthesis of paecilomycine A

✍ Scribed by Goverdhan Mehta; Ramesh Samineni; Pabbaraja Srihari


Book ID
113930375
Publisher
Elsevier Science
Year
2012
Tongue
French
Weight
429 KB
Volume
53
Category
Article
ISSN
0040-4039

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## Abstract The macrocyclic lactone (__S__)‐curvularin (10) and its enantiomer __ent__‐10 were prepared in an enantiodivergent manner from (__S__)‐methyl 7‐hydroxyoctanoate (4), which was easily obtained on two different ways. Esterification of 4 under either retention or inversion of the chiral ce