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An Empirical Correlation between Amide Deuterium Isotope Effects on 13 C α Chemical Shifts and Protein Backbone Conformation

✍ Scribed by Ottiger, Marcel; Bax, Ad


Book ID
120278568
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
200 KB
Volume
119
Category
Article
ISSN
0002-7863

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Novel multidimensional NMR pulse sequences for measurement of the three- and four-bond amide deuterium isotope effect on the chemical shifts of 13Cbeta in proteins are presented. The sequences result in editing into two subspectra of a heteronuclear triple resonance spectrum ¿omega(N), omega(Cbeta),