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An efficient total synthesis of maleimycin

โœ Scribed by Pratap Singh; Steven M. Weinreb


Publisher
Elsevier Science
Year
1976
Tongue
French
Weight
203 KB
Volume
32
Category
Article
ISSN
0040-4020

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## A total synthesis of (+)-isokhusimone 2 has been accomplished efficiently involving the rearrangement of the mesylate 17 as a key step. Ar 1-5 cyclisation of the bromophenol 12 furnished the tricyclic clienone 13 which was subsequently converted into 17.