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An Efficient Total Synthesis of (.+-.)-Lycoramine

โœ Scribed by Chun-An Fan; Yong-Qiang Tu; Zhen-Lei Song; En Zhang; Lei Shi; Min Wang; Baomin Wang; Shu-Yu Zhang

Publisher
John Wiley and Sons
Year
2005
Weight
10 KB
Volume
36
Category
Article
ISSN
0931-7597

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## A total synthesis of (+)-isokhusimone 2 has been accomplished efficiently involving the rearrangement of the mesylate 17 as a key step. Ar 1-5 cyclisation of the bromophenol 12 furnished the tricyclic clienone 13 which was subsequently converted into 17.