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An efficient synthesis of the Lewis X (Lex) antigen family

✍ Scribed by Alexander Toepfer; Richard R. Schmidt

Book ID
108380391
Publisher
Elsevier Science
Year
1992
Tongue
French
Weight
270 KB
Volume
33
Category
Article
ISSN
0040-4039

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A versatile synthesis of the lactoneo-se
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✍ Gerd Hummel; Richard R Schmidt πŸ“‚ Article πŸ“… 1997 πŸ› Elsevier Science 🌐 French βš– 254 KB

Readily available fucosyl ct(l-3)azidoglucose disaccharide 6 is transformed with galactosyl donors 7 and 8 into Lewis X trisacchadde building blocks 9 and 12, respectively, in high yield. Their suitability for the construction of the lactoneo-series glycosphingolipids is demonstrated. For instance,