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An efficient synthesis of pyrrolo[1,2-a]quinazolin-5(1H)-one derivatives with the aid of low-valent titanium reagent

✍ Scribed by Xuan Zhao; Da-Qing Shi


Publisher
Journal of Heterocyclic Chemistry
Year
2011
Tongue
English
Weight
113 KB
Volume
48
Category
Article
ISSN
0022-152X

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✦ Synopsis


Abstract

A short and facile synthesis of 2,3,3a,4‐tetrahydropyrrolo[1,2‐a]quinazolin‐5(1__H__)‐ones and 2,3,3a,4‐tetrahydropyrrolo[1,2‐a]quinazoline‐1,5‐diones in good yields via the novel reductive cyclization of 2‐nitrobenzamides with haloketones or 4‐oxopentanoic acid promoted by low‐valent titanium reagent is described. J. Heterocyclic Chem., (2011).


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