𝔖 Bobbio Scriptorium
✦   LIBER   ✦

An efficient synthesis of pyrimido[4,5-b]quinoline derivatives via three-component reaction in aqueous media

✍ Scribed by Da-Qing Shi; Li-Hui Niu; Hao Yao; Hong Jiang

Publisher
Journal of Heterocyclic Chemistry
Year
2009
Tongue
English
Weight
116 KB
Volume
46
Category
Article
ISSN
0022-152X

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

magnified image

A series of pyrimido[4,5‐b]quinoline derivatives was synthesized by three‐component reaction of 6‐aminopyrimidine, aromatic aldehydes and 1,3‐cyclohexanedione or 5,5‐dimethyl‐1,3‐cyclohexanedione in aqueous media in the presence of triethylbenzylammonium chloride. This protocol has the advantages of higher yields, lower lost, easy work‐up, and environmentally friendly procedure. J. Heterocyclic Chem., 46, 237 (2009).

📜 SIMILAR VOLUMES

Three-component one-pot synthesis of pyr
Three-component one-pot synthesis of pyrazolo[3,4-b]quinolin-5(6H)-one derivatives in aqueous media
✍ Hui-Yan Wang; Da-Qing Shi 📂 Article 📅 2011 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 174 KB

## Abstract A series of 4‐aryl‐3,7,7‐trimethyl‐1‐phenyl‐7,8‐dihydro‐1__H__‐pyrazolo[3,4‐__b__]quinolin‐ 5(6__H__)‐ones were synthesized by the three‐component reaction of aromatic aldehydes, 3‐methyl‐1‐phenyl‐1__H__‐pyrazol‐5‐amine, and 5,5‐dimethyl‐1,3‐cyclohexandione in the presence of sodium 1‐d

Three-component synthesis of spiro[indol
Three-component synthesis of spiro[indoline-3,5′-pyrimido[4,5-b]quinoline]-triones in water
✍ Khosrow Jadidi; Ramin Ghahremanzadeh; Peiman Mirzaei; Ayoob Bazgir 📂 Article 📅 2011 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 100 KB

## Abstract A one‐pot, three‐component method for the efficient and simple synthesis of novel 2′‐amino‐8′,9′‐dihydro‐3′__H__‐spiro[indoline‐3,5′‐pyrimido[4,5‐__b__]quinoline]‐2,4′,6′(7′__H__,10′__H__)‐trione derivatives in aqueous media is reported. J. Heterocyclic Chem., (2011).

Three-component, one-pot synthesis of py
Three-component, one-pot synthesis of pyrimido[4,5-b]-quinoline and pyrido[2,3-d]pyrimidine derivatives
✍ N. A. Hassan; M. I. Hegab; F. M. Abdel-Motti; S. H. A. Hebah; F. M. E. Abdel-Meg 📂 Article 📅 2007 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 537 KB

## Abstract magnified image Reaction of 6‐amino‐2‐methylthiouracil and 6‐amino‐1,3‐dimethyluracil with equimoler amounts of cyclic ketones or cyclic 1,3‐diketones and the appropriate aromatic aldehydes yielded regioselectivity a series of polycyclic pyrimido[4,5‐__b__]quinoline and pyrido[2,3‐__d_