✍ Scribed by Da-Qing Shi; Fang Yang
No coin nor oath required. For personal study only.
A series of 4-aryl-3,7,7-trimethyl-1-phenyl-7,8-dihydro-1H-pyrazolo[3,4-b]quinolin-5(6H)-ones were synthesized via the three-component reaction of aromatic aldehydes, 5,5-dimethyl-1,3-cyclohexandione and 5-amino-3-methyl-1-phenylpyrazole in ionic liquid without using any catalyst. This protocol has the advantages of easier work-up, milder reaction conditions, short reaction time, and environmentally benign procedure.
📜 SIMILAR VOLUMES
## Abstract A series of 4‐aryl‐3,7,7‐trimethyl‐1‐phenyl‐7,8‐dihydro‐1__H__‐pyrazolo[3,4‐__b__]quinolin‐ 5(6__H__)‐ones were synthesized by the three‐component reaction of aromatic aldehydes, 3‐methyl‐1‐phenyl‐1__H__‐pyrazol‐5‐amine, and 5,5‐dimethyl‐1,3‐cyclohexandione in the presence of sodium 1‐d
## Abstract Reaction of 5‐amino‐3‐methyl‐1‐phenylpyrazole (1a) and 5‐amino‐3‐(4‐chlorophenyl)‐1__H__‐pyrazole (1b) with dimedone (2) and __p__‐susbstituted benzaldehydes 3 in ethanol, afforded in all cases tricyclic linear 4‐aryl‐7,7‐dimethyl‐4,7,8,9‐tetrahydro‐6__H__‐pyrazolo[3,4‐__b__]quinolin‐5‐