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An efficient synthesis of pyrano [4,5-c] pyrrole derivatives through microwave—accelerated intramolecular Knoevenagal hetero Diels–Alder reaction

✍ Scribed by Mathesan Jayagobi; Raghavachary Raghunathan

Publisher
Elsevier Science
Year
2009
Tongue
French
Weight
751 KB
Volume
50
Category
Article
ISSN
0040-4039

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✦ Synopsis

Synthesis of novel pyranopyrrole derivatives has been achieved by a one-pot IMHDA reaction of N-substituted aldehydes with various diones in the presence of ethylene diaminediacetate (EDDA) in excellent yields under mild conditions.

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An expedient microwave-assisted, solvent-free, solid-supported synthesis of pyrrolo[2,3-d]pyrimidine-pyrano[5,6-c]coumarin/[6,5-c]chromone derivatives by intramolecular hetero Diels–Alder reaction
✍ Ekambaram Ramesh; Raghavachary Raghunathan 📂 Article 📅 2008 🏛 Elsevier Science 🌐 French ⚖ 139 KB

A rapid synthesis of pyrrolo [2,3-d]pyrimidine annulated pyrano [5,6-c]coumarin/[6,5-c]chromone derivatives has been accomplished in good yields via an intramolecular domino hetero Diels-Alder reaction using microwave irradiation under solvent-free, solid-supported conditions.