## Abstract magnified image Methyl‐3‐(2‐chloroquinolin‐3‐yl)acrylates **5a‐i** on reaction with methyl amine in acetonitrile yielded methyl‐3‐[2‐(methylamino)quinolin‐3‐yl]acrylates **6a‐i**. When, these were followed by the reaction with the Vilsmeier reagent, they afforded methyl benzo[__b__][1,
An Efficient Synthesis of Benzo[b][1,8]naphthyridine-3-carboxylic Methyl Esters.
✍ Scribed by V. Nithyadevi; S. P. Rajendran
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 21 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
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## Abstract A rapid and facile method for the synthesis of novel 5‐amino‐2‐sulfanyl tetrahydrobenzo[__b__][1,8]‐naphthyridine‐3‐carbonitrile derivatives has been developed by the treatment of 2‐amino‐3,5‐dicarbonitrile‐6‐sulfanyl pyridines with cyclohexanone in the presence of anhydrous aluminium c