✦ LIBER ✦

An efficient synthesis of a key intermediate for optically active 5,6-cis-carbapenem antibiotics

✍ Scribed by Norikazu Tamura; Yasuhiko Kawano; Yoshihiro Matsushita; Kouichi Yoshioka; Michihiko Ochiai

Publisher: Elsevier Science
Year: 1986
Tongue: French
Weight: 230 KB
Volume: 27
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)83870-8

No coin nor oath required. For personal study only.

✦ Synopsis

A versatile intermediate ( 18) for optically active 5,6-ciscarbapenem antibiotics was synthesized with a highly regioselective intramolecular aldol condensation as a key step.

📜 SIMILAR VOLUMES

A general approach to trans-carbapenem a

A general approach to trans-carbapenem antibiotics. Enantioselective synthesis of key intermediates for (+)-PS-5, (+)-PS-6, and (+)-thienamycin

✍ Kazuo Okano; Toshio Izawa; Masaji Ohno 📂 Article 📅 1983 🏛 Elsevier Science 🌐 French ⚖ 239 KB

ChemInform Abstract: Efficient Stereosel

ChemInform Abstract: Efficient Stereoselective Route to β-Lactams and Their Application to the Stereoselective Synthesis of a Key Intermediate for Carbapenem Antibiotic (+)-PS-5.

✍ O. MIYATA; Y. FUJIWARA; I. NINOMIYA; T. NAITO 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 44 KB 👁 1 views

ChemInform Abstract: Synthesis of an Opt

ChemInform Abstract: Synthesis of an Optically Active α-Tetralone: A Key Intermediate to Natural Benanomicinone.

✍ T. NISHIZUKA; S. HIROSAWA; M. TSUSHIMA; S. KONDO; D. IKEDA 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB 👁 1 views

An Efficient Synthesis of 3,5-Dimethoxyh

An Efficient Synthesis of 3,5-Dimethoxyhomophthalic Acid, a Key Intermediate for Synthesis of Natural Isocoumarins.

✍ Aamer Saeed; Nasim H. Rama; M. Arfan 📂 Article 📅 2003 🏛 John Wiley and Sons ⚖ 107 KB

An efficient synthesis of 3,5-dimethoxyh

An efficient synthesis of 3,5-dimethoxyhomophthalic acid, a key intermediate for synthesis of natural isocoumarins

✍ Aamer Saeed; Nasim H. Rama; M. Arfan 📂 Article 📅 2003 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 40 KB

## Abstract 3,5‐Dimethoxyhomophthalic acid was prepared efficiently in three steps, from 3,5‐dimethoxybenzyl bromide __via__ rhodium‐catalyzed direct carbonylation to 3,5‐dimethoxyphenylacetic acid followed by successive __o__‐formylation and oxidation. Isocoumarins related to agrimonolide and achl

Simple synthesis of 2-acetyl-5,8-dimetho

Simple synthesis of 2-acetyl-5,8-dimethoxy-3,4-dihydronaphthalene, a key intermediate for the synthesis of optically active anthracycliones

✍ A.V.Rama Rao; V.H. Deshpande; B.Ramamohan Rao; K. Ravichandran 📂 Article 📅 1982 🏛 Elsevier Science 🌐 French ⚖ 113 KB