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An efficient synthesis of 5,6-dihydrobenzo[h]quinazoline derivatives under solvent-free conditions

✍ Scribed by Lijiu Gao; Honglou Ji; Liangce Rong; Hongxia Han; Yanhui Shi; Shujiang Tu

Publisher
Journal of Heterocyclic Chemistry
Year
2010
Tongue
English
Weight
100 KB
Volume
47
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

magnified image An efficient and convenient method for the preparation of 5,6‐dihydrobenzo[h]quinazoline derivatives by the multicomponent reactions of aromatic aldehydes, 3,4‐dihydronaphthalen‐1(2__H__)‐one and urea or acetamidine hydrochloride, in the presence of sodium hydroxide under solvent‐free conditions was reported. This method has the advantages of excellent yields, mild reaction conditions, easy work‐up, and environmentally friendly procedure. J. Heterocyclic Chem., (2010).

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